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Qualitative simulation of large and complex genetic regulatory systems

H. de Jong, M. Page

Proceedings of Fourteenth European Conference on Artificial Intelligence, ECAI 2000, W. Horn (ed.), IOS Press, Amsterdam, 141-145, 2000


Modeling and simulation techniques developed within qualitative reasoning might be profitably used for the analysis of genetic regulatory systems. A major problem with current qualitative simulation techniques is their lack of upscalability. We describe a method that is able to deal with large and complex systems, and discuss its performance in simulation experiments with random regulatory networks.