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Multiscale modeling of alternative splicing regulation

D. Eveillard, D. Ropers, H. de Jong, C. Branlant, A. Bockmayr

C. Priami (ed.), Computational Methods in Systems Biology, CMSB-03, Lecture Notes in Computer Science 2602, Springer-Verlag, Berlin, 75-87, 2003

Alternative splicing is a key process in post-transcriptional regulation, which allows obtaining different kinds of mature RNA. We develop models of the alternative splicing regulation at different scales (single-site vs. multiple sites) in a constraint programming framework.